17 Notes From San Francisco.
They All Point to One Thing.
Straight from @gregisenberg's "In the Trenches" thread. We pulled the 7 that change what YOU do.
1
GI
Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"I had lunch with 3 billionaires. All of them are buying SaaS companies and rebuilding them agent-first."
🎬 Flash real tweet first (Screenshot 1, note 1) → morph to this card → highlight swipes on "rebuilding them agent-first"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"I heard the phrase 'agent debt' for the first time. Hack an agent workflow together fast, prompts conflict, the memory gets polluted, tools overlap. 6 months later the agent is doing weird things and nobody knows why."
🎬 Flash real tweet first (Screenshot 2, note 16) → morph to this card → highlight "agent debt" then "nobody knows why"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"MCP came up in literally every conversation. The ones exposing their product as MCP get pulled into deals they never pitched. The rest are becoming invisible to agents. This is the new SEO. If agents can't find you, you don't exist."
🎬 Flash real tweet first (Screenshot 1, note 4) → morph to this card → highlight "If agents can't find you, you don't exist"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"'Which model do you use' is being replaced by 'which model for which task.' Model loyalty kinda feels dead."
🎬 Flash real tweet first (Screenshot 2, note 7) → morph to this card → highlight "Model loyalty kinda feels dead"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"Frontier model companies can see API calls and token counts. They can't see the actual workflows. If you're deep in a niche, that's incredibly valuable. Usage intelligence is the new alpha."
🎬 Flash real tweet first (Screenshot 1, note 2) → morph to this card → highlight "Usage intelligence is the new alpha"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"The hottest role in SF: the forward-deployed engineer. The person who sits between the agent and the customer, making sure everything actually works."
🎬 Flash real tweet first (Screenshot 1, note 6) → morph to this card → highlight "making sure everything actually works"
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Greg Isenberg ✔
@gregisenberg · In the Trenches, SF
"Walking around the Mission: the street-level businesses, the taquerias, the barbershops, the laundromats. None of them use any AI at all."
🎬 Flash real tweet first (Screenshot 2, note 15) → morph to this card → highlight "None of them use any AI at all" · this is the close